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a ghastly flu-like feeling after far too much partying, self-medication, boozing etc. Self afflicted illness.
by Snozloz August 23, 2007
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2
The sickness that onsets, usually on a Monday, after a weekend full of partying and doing drugs.
Calling in to work -

Partier: Boss, I got the party flu I'm not going to be in today
Boss: No problem man. I'm just getting over my party flu from last weekend. It was hardcore.

Partier: Thanks. See you tomorrow
by big booty ho's January 23, 2017
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