Off the 2 is to refer to someone who is acting or is, off 2 pills. Acting sluggish or drowsy. It is also used to say this person is acting weird as if they are off substances.
by HoodTranslater January 22, 2021
Get the Off the 2mug. by Custard October 5, 2006
Get the mugging me off like a 2 bitmug.