when you have a spoonful of sugar to help the medicine go down, and the combination of the two ends up giving you mad diarrhea
guy 1: hey man, heard you haven't been too well lately.
guy 2: yeah dude, got a serious case of the mary sloppins
guy 2: yeah dude, got a serious case of the mary sloppins
by shaneskillz1 December 31, 2010
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mary sloppins
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