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Da "feel-good" chemical in yer brain dat temporarily lifts yer mood whenever something positive/exciting/enjoyable happens, but den ya feel like a complete dope after da "high" wears off.
I loved ridin' da roller-coaster a whole bunch, but den afterwards I had a brain-chemical letdown --- sounds like a classic case of "Dopeamine crash" to me.
Dopeamine by QuacksO July 31, 2018
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A word similar to the slang "Dope" meaning Cool or Great. It is often used for emphasis.
Frank: Hey Jimmy, Golf Course party tonight!
Jimmy: Dopeamine!
dopeamine by nubatron 2000 May 3, 2006

dopamine detox 

During a dopamine detox, a person avoids dopamine triggers for a set period of time — anywhere from an hour to several days.

The dopamine detox requires a person to avoid any kind of arousal, specifically from pleasure triggers. Anything that stimulates dopamine production is off-limits throughout the detox.

Ideally, by the end of the detox, a person will feel more centered, balanced, and less affected by their usual dopamine triggers. Allowing them to pursue their goals with minimal distraction
Hey alan: im doing a dopamine detox so I can become a successful online dropshipper and not have my mind on boobs

Alan: dude I told you to stop watching Andrew Tate videos It's just a phase...
dopamine detox by Rapidshark112 April 21, 2023

Dopamine 

Yeah dude I'm high on dat dopamine.
Dopamine by Optional Fingers July 10, 2017

dopamine 

The root of all addictions.
Dopamine is responsible for the "high" we get every time we do something pleasurable
dopamine by Dubiks August 28, 2018

Dopamine Blast 

A sudden feeling of joy brought on by dopamine being released in the brain. Its a sudden feeling of happiness caused by such things as shopping, doing well on a test, and smoking up. Any time you notice a sudden, positive mood alteration, you are experiencing a dopamine blast.
Kelsey: "I just got an A+ in orgo, dopamine blast!!!".

Nick: "What a nerd..."

Kelsey: "Whatever, someone needs to get off the haterade".
Dopamine Blast by kawar November 7, 2009

dopamine 

a chemical that is responsible for "love at first sight"
as explained in charlieissocoolike's video "Chemical Love"
it makes you infatuated with somebody.
it is also the chemical that makes you sort of high and happy.
DUDE 1: "i think i love her"
DUDE 2: "no you don't, you've only known her for like a week."
DUDE 1: "but she's perfect"
DUDE 2: "that's the dopamine talking!"