Skip to main content
(noun, singular). An abbreviation of diphenhydramine, the active ingredient in Benadryl, an antihistamine. A common and notable side effect of this drug is sedation, so many people will take (and can buy over the counter) these in tablet form in order to get some shut eye. It's not often that it is misused since the sedative effect is actually rather unpleasant for most people and feels as if one "can't really get enough air," even though this is merely a feeling and not medically accurate.

Diphens should also be taken by those having a severe allergic reaction (before an epipen, if possible and appropriate) in order to avoid full-on anaphylaxis. Depending on the presentation and speed of the progressing allergic reaction, it may be necessary to simply give the epipen immediately.
"I can't sleep - do you know where the diphens are?"

"I was only able to sleep last night after I took a diphen."

"Without diphens, my anxiety keeps me awake almost all night and I never sleep very well."
diphen by cardiogenix December 16, 2013
diphen mug front
Get the diphen mug.
See more merch

Diphenylprolinol 

Diphenylprolinol is a mild stimulant that is a norepinephrine dopamine reuptake inhibitor. It's a research chemical and cognitive enhancer.
Oral dose (tentative)
Light: 15 – 20 mg
Common: 20 – 40 mg
Strong: 40 – 50+ mg

Duration is 3 to 6+ hours.
I took 30mg of Diphenylprolinol and I was energetic and studying.
Diphenylprolinol by HawaiianPunch1 February 18, 2022

Diphenylchloroarsine 

Irritant that can bypass gas masks and make soldiers remove them exposing them to more deadly gasses. It is a maskbreaker gas
I took off my gas mask because there was diphenylchloroarsine. Now I’m dead.
Diphenylchloroarsine by Werrywit September 22, 2022

dyphen the kyphen 

To smoke a large amount of marijuana (Kyphen)
Kennedy: You guys wanna dyphen the kyphen?

McKee: Yeet!!
Bill: infinity!!!
The coolest fucking person you've ever met, he is kinda like a legend, everyone knows who he is
Person1 :Damn dude is that Dipen there?

Person2: Yea what a stud
Dipen by Dipen® January 4, 2017

Diphenhydramine

Diphenhydramine is a drug used as a sleep-aid. It is often used as a recreational drug that is cheap and effective.
I've used diphenhydramine as a recreational drug before. If you want to you need to find out what high dose is right for how much you weigh. When I used it my light moved around, when I looked at my wall there were hundreds of flys all over it and it sometimes looked like my walls were smoking. I could barley walk and I didn't really know what I was doing all that much.
Diphenhydramine by Your man! 325😉 September 21, 2016
A combination of dipshit and dickhead, this term is generally used when a person becomes so frustrated at another, that their words become scrambled.
No, I will not lick your butt you diphead!

Rose and Nat are such dipheads, they think they rock the PIC.
diphead by IDWaN June 4, 2009