ass-wine Share definition Flag The fluid that leaks from ones' ass causing both discomfort and staining of the underpants. I had to change my underpants twice yesterday due to the higher than average amount of ass-wine I was leaking all over them. Also: I was in discomfort. ass-wine by adam+ October 15, 2007 0 0 Get merch Get the ass-wine mug. Buy Now — $32.95 See more merch