Vegas Depression 

Also known as "VD" (commonly mistaken with venereal disease), Vegas Depression comes about about a month or less after coming home from a trip to Las Vegas. It will hit you out of the blue and it is hard to get rid of. A common symptom of VD is going onto Expedia.com or priceline.com to look at prices of trips. The only cure* to Vegas Depression is to go back to Vegas. VD is something you cannot get rid of no matter how many times you go.

*cure- meaning not so much of a cure but something to help the pain (only while you are in Vegas)

Tommy: "Yo, I have VD really bad!"

Will: "What the fuck, that's sick!"

Tommy: "No, I have Vegas depression. I was sitting at my shitty job today and it just hit me out of the blue."

Will: "Shit, I'm depressed now."

Tommy: "Oh well, I guess we can check prices on Expedia."

Will: "Word."

Vegas Depression by Okyamot February 19, 2009

Post-Vegas Depression syndrome 

The condition that is felt upon returning from a Las Vegas vacation back to real life. Usually lasts 4-5 days. Symptoms include staying in bed all day, heavy drinking by yourself, and attempts to book future visits in the near future. Productivity at work goes down the toilet...

Man that Vegas trip was great, but I think I'm suffering from Post-Vegas Depression syndrome.

Post-Vegas Depression syndrome by Dirty Vegas July 21, 2005

Post Vegas Depression (PVD) 

Depression experienced after an awesome weekend of drinking, smoking, dancing, gambling, and fucking in Las Vegas.

Damn, homie... Post Vegas Depression (PVD) hittin' hard now that I'm back at work.

Post Vegas Depression (PVD) by serleomar October 20, 2008