1. n. - the condition by which your upper lip, having been subjected to the arid, air conditioned, cigarette infused air of Las Vegas, combined with excessive consumption of alcohol and/or other substances dehydrates to the consistency of a flaky, shriveled raisin.
Dude, I tried to make out with this chick in the club, but the both of us had such a bad case of Vegas Lip, it was like kissing sand.
by OphidianX June 3, 2011
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Sweating of the upper-lip which is caused by the hot desert climate of Las Vegas in conjunction with amphetamine or cocaine use.
“You good man? Your lip is sweating right onto the blackjack table!”

I’m straight. All that speed gave me a case of the Las Vegas lip sweats”
by blumpkinben June 28, 2018
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