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1) To remove hair from the anus in preparation for rear-entry jankage, usually with a pair of tweezers.

2) An exclamation redolent of the sinking anticipation of such an activity.
Dude: Man, did you see the 400 pound gorilla in Jackie's basement?
Man: Yeah, Dude, she's janked for sure. I bet she's totally tweedged.

F. Michael Haynie: Um, sorry, man, I'm Equity.
Jeremy Dobrish: Dah, TWEEDGE!
by SuperStudPony August 30, 2010
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