1) To remove hair from the anus in preparation for rear-entry jankage, usually with a pair of tweezers.
2) An exclamation redolent of the sinking anticipation of such an activity.
Dude: Man, did you see the 400 pound gorilla in Jackie's basement?
Man: Yeah, Dude, she's
janked for sure. I bet she's totally tweedged.
F. Michael Haynie: Um, sorry, man, I'm Equity.
Jeremy Dobrish: Dah, TWEEDGE!