An acronym that stands for Truly Laughing Out Loud. Created because the popular "LOL" and "haha" have recently evolved into a way of acknowledging what someone says to you on AIM. TLOL indicates that you are, in fact, laughing out loud.
"I just got back from the movies"
"lol cool" (NOT actually laughing out loud)
"...then I stepped on the cat's tail"
"omg tlol" (TRULY laughing out loud)
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.