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When someone takes too much (or a mix) of any supplement(s) for any purpose (although it relates predominantly to supplements of the 'work-out' variety) and their body reacts in a very violent and severe way usually involving the excess supplements being expelled from both the mouth and the anus. NB Supplement Pop is usually preceded by a moment of total clarity.
Gym Junkie #1: Damn man, I had soooo much of that Mega Whey I got massive Supplement-Pop!

Gym Junkie#2: Damn Brah, that sucks! Did it come out your ass and your mouth?
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