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Sisto is the type of guy to break your heart unknowingly. Or, sometimes he will but you’ll never really know what he’s thinking or feeling. An overall great guy, very attractive and tall but will not hesitate to drop you and leave you. He’ll talk to you for a little, then end up finding someone better and ghosting you. Of course he’s a high school jock... he’s used to being hit on and taking advantage of girls beneath him.
Girl: Sisto said he was going to bed but stayed up talking to that bitch Bethany!
Girl 2: You should’ve known that he was a heartbreaker.
by iloveyouandyoursmile September 29, 2019
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The younger brother of former space pirate, Brak. Long ago he was Brak's second in command, helping him commit evil insidious acts, but radiation from a meteor shower had riddled them harmless. While Brak became retarded, Sisto became mute (though he tends to respond with to people with fart noises).

Though it is still uncertain what species Brak and Sisto actually are, their kind have been refered to as catmen on numerous occasions. Though the two are almost identical, Sisto is much shorter and wears a red uniform in contrast to Brak's blue uniform. Supposively, he was killed off in ep 18 when aliens beamed him up as their chosen food source.
Dad: "Do I smell the stink of Jealosy?"
Sisto: *farts*
~episode 4 War Next Door
by Autumn Rayne April 25, 2005
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It comes form the latin name “Sixtus” which means sixth. Italians adopted the name as “Sixto” then changed it to “Sisto”

Other counterparts of this name are “Sixto, Seisto, Cesto, and Xisto”

Pronounced as (See Stowe)
“This is my sixth child, I don’t know what to name him!”
“Name him Sisto for sixth”
Good idea!”
by Tristen Forest May 26, 2019
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