The condition of being so damn tired that suddenly everything is funny. A deeper condition than the Late Night Giggles.
Dude 1: Why are you laughing so much at this? It wasn't even funny!

Dude 2: I'm sorry man, it must be Sacramento Syndrome, I gotta go to bed.
by Rey Dragon Azul December 6, 2022
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the act of taking yourself way too seriously after reaching the age of eighteen
Person 1: "Wow, she's a really good looking girl"

Person 2: "Yeah, too bad she's into me because you're only 17"

Person 1: "Wow, that pathetic Sacramento Syndrome comes out of you a lot doesn't it?"
by jdiggitydog916 December 12, 2010
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