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Southern Illinois University Edwardsville is the high class version of SIUC. SIUE students are much smarter, better looking, and more talented than SIUC's students. SIUC students can party...but that's about it. SIUE's students can party and get A's. Their pretty much the s***. With SIUE's popularity increasing, SIUC is now at the bottom of the barrel. WE ARE.....THE E!!!!!!!!!!
Guy 1: You go to SIU?

Guy 2: Yea, SIUE not SIUC.

Guy 1: GOOD! Nice to know you're not a piece of s***.
SIUE by jamesfrank October 19, 2010
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Along with SIUC it is basically a glorified community college. The campus is large and wooded but that is about all they have going for them. The social scene sucks and most people want to transfer after the first semester. The degree is near worthless and you need a 15 at most on your ACT to get accepted. As a whole the school is a joke.
I didn't get accepted to any good schools. I guess I'll go to SIUE, at least it isn't Carbondale.
SIUE by Sucks to Suck June 10, 2011
A dude who loves to drink and stay at home watching TV. (refer to Couch Potato)
"Yo where is John?"
"He's at home being Siuea"
Siuea by T-Rex Mayn March 4, 2010

ufhlfuhefuheuvnzhouehovi10918980180192801jfjkelkjfh lzusefhzl siuefhzvnsoeifuhzovsneifuznhseofiuzsoevnufizhf 

*falls down stairs* ufhlfuhefuheuvnzhouehovi10918980180192801jfjkelkjfh lzusefhzl siuefhzvnsoeifuhzovsneifuznhseofiuzsoevnufizhf
“You guys need to stop talking I’m really siued right now.” -Mr Fisher (Poway High School)
siued by Green Onion June 4, 2018
Students of The Saigon International University (SIU), an international university founded in Vietnam.
I am a SIUer!
SIUer by Lucaslucasvj November 28, 2021
siueli is a fucking retard. the dumbest coconut that prolly has 16 stds. he dresses homeless and sucks at downball. the typa guy to talk the meanest shit on fortnite and then get shit on and say "oh i was laggin" hes got mad anger issues and rages all the time
"siueli is fuckin autistic"
siueli by SiuelisAutistic November 22, 2023