NejiSaku is a shorter way of saying "Neji x Sakura" It is a pairing that consists of Sakura Haruno and Neji Hyuga from the anime/manga Naruto.Although (sp?) compared to other pairings such as NejiTen,or SasuSaku NejiSaku may seem "small-ish" it is actually quite popular among fans in fanart and doujinshi.
by Fandom's Cheese October 23, 2009