When something or someone ruins your good mood. Its like your vibe was shot as soon as you see this person or as soon as you walk into a certain room.
Student 1: *walks into 3rd hour Am. lit.*
Student 2: "man I hate this class"
Student 1: "yeah I know this class and Ms. P murder my vibe."
Student 2: "man I hate this class"
Student 1: "yeah I know this class and Ms. P murder my vibe."
by G&Z June 1, 2015
Get the Murder my vibemug.