A combination of "mah" (my) and "nigga", with the catch-all "izzle" ghetto suffix.
"Wassup, manizzle? I shonuff ain't seen you fo longass time."
by Altratronic October 20, 2007
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From the Backround of Nigro folk, It was founded on the basis of use in Rap, and Gangsters chizzlin' in the hizzle fo shizzle.
Now wait justa manizzle!
by A Cracka February 16, 2005
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As in the AOL commerial when Snoop Dog said, "Now wait just a manizzle!"
by Connah December 5, 2003
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