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Lethal Dose, 50%. Refers to the dosage of a given drug required to kill 50% of a test population. The LD50 is usually measured in units of mass of drug per units of body mass; for example, mg/kg. This type of measurement is used to help ensure that the size of the specimen has no effect on the dosage measurement, as a large specimen can generally take a larger dose of a toxin without fatal effects. The measure is often known colloquially as the "semilethal dose;" while it may not always be lethal to a given subject, it will be lethal around half the time.
The LD50 for nicotine in rats is around 50 mg/kg, but it is only 3 mg/kg in mice. What's the LD50 for humans, you ask? Well, if you're willing to participate in the experiment to find out, go buy some cigarettes and knock yourself out (literally).
LD50 by progamer124 May 16, 2004
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Sometimes used to describe the percentage of a woman's brain that is missing. The root of this comes from the abbreviation LD50 or Lethal Dose required to kill half of a population. In this case the LD stands for Lacking Discernment. Depending on the amount of brain missing, the number 50 can be substituted with any percentage greater than 50. Can be used in casual bar conversations so that no attention is drawn by the woman of topic.
Hey Ben, that girl is definitely LD50. She's so fucking stupid that I've caught her cheating on me 3 separate times and she still denies it!
LD50 by Bojangles0928 January 18, 2010
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Mudvaynes first official record studio album released on august 22 2000 and a lethal chemical dosage. Chemical dosage definition: Lethal Dose, 50%. Refers to the dosage of a given drug required to kill 50% of a test population. The LD50 is usually measured in units of mass of drug per units of body mass; for example, mg/kg. This type of measurement is used to help ensure that the size of the specimen has no effect on the dosage measurement, as a large specimen can generally take a larger dose of a toxin without fatal effects. The measure is often known colloquially as the "semilethal dose;" while it may not always be lethal to a given subject, it will be lethal around half the time.
*in science class* teacher: “today we’re talking about lethal dose 50 or ld50. Me in my mind: brbr deng brbr deng brbr deng brbr deng dig! dig! dig! dig! dig! dig! Noooooo!!!!!!!!!!!!!
Ld50 by Nascarfan2007 April 15, 2023

Gayborhood 

N. A neighborhood containing homes, clubs, bars, restaurants, and other places of business and entertainment that cater to homosexuals.
"They've opened up a new club in the Gayborhood called the Male Box."
Gayborhood by Mia Shields January 6, 2006
Word of the Day on July 14, 2026
A small piece of information. Derived from the word ken, used often in the scottish language and is synonymous with knowledge.
Person 1: "Hey I don't get this shit. How do you solve this problem?"
Person 2: "I got that one. Give me some kenlets on this assignment and I'll help you w/ that one."
kenlet by Norma Y. October 8, 2005
Word of the Day on July 13, 2026

I mean I guess bro

a word of expression to when you give up on comprehending someone's words of ignorance, stupidity, absurdity or are too exhausted to formulate a proper response.

Commonly seen in TikTok comment sections in replies to lazy attempts at humor, overconfidentally incorrect statement, or an over-the-top comment or when someone completely misses the mark on something.
"actually... incorrect statement, hope this helps!"
"I mean I guess bro"
Word of the Day on July 12, 2026

abandonware 

n. software that is no longer sold or supported by the original publisher / developer, often found as free downloads on the internet because it cannot be obtained elsewhere. Not legal, but often seen as morally acceptable because the company that made it is no longer selling the title, nor releasing it as freeware, therefore abandonware is "keeping the game alive", so to speak.
Doom II is not abandonware because id still sells it, while The Incredible Machine is not sold, therefore is abandonware.
abandonware by Spoom October 24, 2003
Word of the Day on July 11, 2026