A Karen who is a pill popper, as opposed to most Karens, who are simply a pill.

Reference to the Will and Grace character.
“Yeah, she shows up late to work a bottle in. And I’m talking both vodka AND pills. Such a. Karen Walker.”
by TK2000 October 30, 2023
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The alcoholic, pill-popping, sexaholic, bisexual, lovely socialite that Megan Mullally plays on the show 'Will and Grace'. Yayy for Karen.
I was drinking a martini last night, and I looked exactly like Karen Walker.
by Jaci <3 December 2, 2005
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Short fat northern hormonal sociopath, who has been convinced her daughter is a bit of a minx. A further definition is a brutal and spiteful human being who imparts her long seen life failings as a parent and a women on others through the use of coarse and unfair tactics and words. In summary, a self centered and delusional hormonal breeder of sluts.
You're a useless piece of shit, said Karen Walker Digits to a member of her team, as her daughter walked in with another brown baby.
by Afghan Will January 4, 2018
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