verb one-guyed or one-manned is notably used on Twitch and refers to when a streamer with a sizable chat gives attention to a chatter by arguing with that chatter as if that chatter speaks for a large amount of chat.
XQC and Malena tend to go on long rants because they let themselves get one-guyed often. It's annoying because you can sit there for minutes wondering who they're talking to.
Club Ho 1- Hey that guy who's 57 just asked me out. I'm 23 and hot. He's such a MANther!
(giggle)(spills a bit of Red Bull+Vodka)
Club Ho 2- Tee hee hee! So like Blake said-
Bartender- Would you two bitches shut the hell up? It's not MANther, retard. That's a feline term. Guys are dogs, not cats. The actual term is "Guyena"