Guagüis Share definition Flag Mexican/Latin term used to define oral sex performed by a female. "That chick Tina gives a mad Guagüis!""¡Esa vieja da un Guagüis bien macizo!" Guagüis by Zavala82 May 22, 2013 0 0 Get merch Get the Guagüis mug. Buy Now — $32.95 See more merch