1. When the electricity goes out, and people who have been used to always working begin to freak out.
2. When people used to constant electronic access, lose their devices (temporarily or permanently) and go through rapid withdrawal.
1. Ann: Have you seen the way Bob has been acting lately?

Jake: The power is out. What do you expect? It's Grube Syndrome.

2. Robby: Why is Andrew acting so crazy?

Allen: His parents took away his laptop because he got a C in Economics. He's going through some serious Grube Syndrome.
by millenialwatchdog March 30, 2011
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(origin: teutonic, germanic) the process of: filling your belly with mid-shelf liquor and greasy food; allowing the concoction to ferment in your gastric fluids for more than twenty-four hours; mounting a bucket with the intent to defile; defiling the bucket; and violating your unsuspecting concubine by force-feeding him/her the muddle immediately after he/she accepts your nut in his/her person.
Ex. Right after the Honorable Aldonquin Calhoon got porked to be damned, I, much to his dismay, bestowed upon him the infamous Messy Grube. After, I reveled in his cough, gag, and immediate death.
by Kristen Kellam January 13, 2005
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a cheap picture taken in a studio somewhere in the south of france, liebe grube is a mysterious woman that sends post-cards to people claiming to be their "little cousin sarah." once, when liebe grube's photo was scanned into a duel printer-scanner-fax machine, she continued making copies of herself until the machine was unhooked and rebooted.

local myth attributes the curse of liebe grube to the murder of a young girl by her rabies ridden cat named hazel.
susie could not go to sleep because the myth of liebe grube her mommy told her made her worry about wetting the bed.
by witn June 23, 2006
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