a. To have a big ol'booty all over yo shit.
b. To obliterate someone so bad that there is nothing left for them to do but quit the game.
c. To have someone or something violently shaking their ass all over you.
"Daaaaamn, nigga gettin twerked on and she sweatin".
"Get twerked on. Quit the fucking game".
by Tranzparent August 18, 2016
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