1) A phrase one would use toward another person, telling them to not spoil their good mood.

2) used in situations where phrases like "stay away from me" would be used
Professor, don't kill my vibe by assigning that 20 page report on my birthday.

Sometimes I need to be alone, bitch don't kill my vibe.
by Panthers2829 July 7, 2014
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Don't mess or interfere with their current emotional atmosphere and feelings. Popularized by a famous song by Kendrick Lamar.
*girl 1 is partying and drinking a day before a college test*
Girl 2: "Hey, we should get some sleep before the test, I know this is a good moment and all..."
Girl 1: "Bitch, don't kill my vibe!"
by Chris's_Zen May 15, 2013
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