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A name used for the ever growing more violent; Danville, Illinois. With shootings and opiate trade (heroin) becoming an everyday occurrence in most parts of the city, locals and people who grew up there are starting to liken it to a combat zone. Hence Afghani-Dan.
"I hear you're heading to Afghani-Dan for thanksgiving. You better have body armor on."

"Did you hear about the police standoff after a cop got shot in Afghani-Dan?"
by IraqTANKER July 14, 2014
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