when an annoying bitch named beverly thinks you are friends with her and shes mexican so she trys to incorporate her culture by changing friend to amigo.And from that day on she has a nickname for you and the phrase best amigo...
beverly:BURGER QUEEN YOU ARE MY BEST AMIGO!!!!! Alana:(Dear lord help me)......Hey beverly my best.......amigo...
by swiggityswoogity69 November 26, 2019
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The cock and balls, what else could be so inseparable? They just cuddle up together in the scrote. God gave man the three amigos to prevent loneliness.
Brosif #1: hey man you wanna chill today?
Brosif #2: nah man I’m extra tired, all the energy I have left is for my 3 amigos, imma tug a few hot ropes out and sleep.
Brosif #1: no sweat man I know how those days go.

Example 2
Bradley cooper had a very saggy 3 amigos, he could do a squat and the 3 amigos could touch the floor with steez
by SlipperyYMCA January 29, 2022
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A close friend; equivalent to "my nigga"
I grew up with Andre, that's my amigo!
by EBMRue December 26, 2013
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When you are going to sleep with a very attractive women but are self conscious of how small your penis is, so right before entry you put your two thumbs on your penis to make it feel bigger.
Man I used the three Amigos on this girl last night. It was so good I even made her finish.
by Las Fuher February 18, 2022
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The most amazing people in the whole universe these people have know each other since pre k. Nothing can break up this friend ship they are usually the coolest people ever and very funn and smart
by TheThreeAmigos December 13, 2017
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Your negro amigo is the mix between a mexican and an african american. Your Negro Amigo often is there for you during the tough times, Although he rarely has a high IQ level.
You can always trust your negro amigo.
by maxatron July 30, 2009
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A group of 4 friends who spend every waking moment with each other.
Don't invite Jess! If we do it won't be the 4 amigos anymore, lets all just stay home and play mlb 2k6.
by mlb2k6 August 8, 2008
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