by Ghetto-Syndrome Hater March 11, 2017

The most ugliest person ever ... they like to rub their ass all over you , jump over seats , and dress like cartoon characters.
Melissa is such an ugly ass bitch
by Anonymous 1204 May 4, 2018

A Melissa are someone who can easily fall under pressure and become depressed. Results to taking unprescribed medicine, or drinking. They will want to cling to your side because they feel dependent, especially in hard times at school. Best friend will be a cat, probably for life. Walks slumped over, and kills all happy moods of others. A "Buzzkill"
by RachelBlackburn May 14, 2011

An awful person with anger issues. Very petty, insecure, and self-loathing. Is nice to your face, but very toxic and back-stabbing. Abuses their kids and neglects them to sell drugs. Don't be a Melissa.
Why did you just hit your child all because they were talking to someone you don't like? Stop being a Melissa!
by gruesomegordy January 2, 2021
