E is commonly used as a response to something you don't have a proper response for, it is also commonly used in 'dank' or 'deep fried' memes. Apparently the meme is associated with Lord Farquaad (the main antagonist of the popular film Shrek) and due to the absolute chaos that is meme culture a YTP artist decided to make a video titled "Shrek but only when Lord Farquaad says E" The letter was a meme before this but the video brought it back into meme culture.
by wiglygigli February 23, 2021
Get the Emug. 
eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee
Person 1: no more being stupid
Person 69: eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee
person 1: noob the limit is 1500
Person 69: eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee
person 1: noob the limit is 1500
by COCACOLAESPUMA December 4, 2020
Get the emug. EeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeEeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeerreeeeeeeeee
by Photo relisted meme ššš December 14, 2022
Get the Emug.