An action akin to the high-five or the handshake. The act of touching fists knukle-to-knuckle in greeting or departure. In 2003 this action was accompanied by the phrase "knuckle-up" but has since just become the motion without the phrase. The first instance of this action and phrase was in Dallas, TX in the mid-90's and has since become a common gesture in most public forms of transit in NYC.
by super steve August 31, 2005
by MS. BOUNCE DAT AZZ July 12, 2006
Guy 1: Did you see Stacey?
Guy 2: Yeah, total nipple slip! I'm totally going to knuckle up to that later
Guy 2: Yeah, total nipple slip! I'm totally going to knuckle up to that later
by leobaby1 November 18, 2011
When two men choose to engage in mutual masturbation, implementing a "thumb war" grip and jerking themselves off simultaneously, locked at the knuckles.
by DaXymbiont February 07, 2018