Pepperoni's Disease

The unfortunate souls who are diagnosed with this disease are commonly referred to as captain hook.

Pp go down

Girl 1: I was having sex with my boyfriend for the first time and his penis curled backwards.

Girl 2: Oh yeah, he must've had pepperoni's disease

by Captain Hook 2006 December 19, 2022

Heart Disease

One of the two ways an American can die. The other one is guns.

I think I have heart disease.

by ImNotA_Tree December 20, 2022

Lack of Girlfriend disease

It is fatal, the victim will suffer intense heartbreak until receiving medication, which is obtained from seeing their partner.

“Help, i’m going to die, i haven’t seen my girlfriend in a week, i think i have lack of girlfriend disease”

by ashl3yz August 31, 2023

The IG Disease

Originated from the song “Clout” by Offset featuring Cardi B

Someone who has this disease is basically addicted to instagram and cares too much about other peoples lives and what other people think of them. Once this disease is contracted there is no cure for it

Nah bro she def got the IG disease she always givin af about other peoples lives and opinions

by MrFlamin September 3, 2023

HTTP disease

A very rare disease (there are no known cases of it) where you involuntarily say something similar to "404 page not found" upon encountering a situation you are not prepared for.

Person 1: Hello, I have HTTP disease.
Person 2: I don’t believe you and I now hate you for lying!
Person 1: 404 page not found.

by PlaceReporter99 September 12, 2023

soundcloud disease

idk but i heard it kills people by listening to bad music

boy get out with yo SoundCloud diseased phone

by gen J September 12, 2023

Disease

Being a ginger.

Yeah she was born with a disease

by void! September 12, 2023