syke!

Syke is said (or yelled) as sign of opposition to what was last said by the one who says (or yells) it. Basically, if I say I have a nice girl, followed by a syke, it means my chick is a whore. :-) You can also say "not", "nae" or "or...".
Ryan : Your bae gave me a call, she wanted to see me.
Marley : For what?
Ryan : She was flirting with me.
Marley is really surprised!
Ryan : Syke!
Marley slaps Ryan and walks away.
by LebbEx February 21, 2019
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