Short for "it's a" popularized by 21 Savage. In a word ISSA the first 2 letters "IS" literally look like 21 if it was mirrorized.
by Issacool July 8, 2018
Get the Issamug. Something you say to your friends over relatable topics.
Most of the topics are over guys, exes, or just stupid things in general.
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Credits to creators of this definition... Alexandra Mackenzie and Hannah
Feel free to add us, the crackheads on Snapchat
-Alexandra (Alley) @alley_t03
-Mackenzie @mackenzie4125
-Hannah @hannahpilgrim16
Most of the topics are over guys, exes, or just stupid things in general.
.
.
Credits to creators of this definition... Alexandra Mackenzie and Hannah
Feel free to add us, the crackheads on Snapchat
-Alexandra (Alley) @alley_t03
-Mackenzie @mackenzie4125
-Hannah @hannahpilgrim16
by crackheadlife101 November 22, 2019
Get the ~issa mood sis~mug. A Muslim that will blow up your country and will tell you to kill yourself
But he is friendly all the time
But he is friendly all the time
Issa is a good person
by Issa21x April 4, 2022
Get the Issamug. by anonymous January 17, 2024
Get the issamug. 

