wuey Share definition Flag Wuey is a mexican slang word that means "Dude" for gringos and "Nigga" para los negros. Que ondas wuey! Chale wuey... Hey wuey come here wuey by Mr.78 June 30, 2016 0 0 Get merch Get the wuey mug. Buy Now — $32.95 See more merch