meme-killer 

A meme-killer is a person that overuses a certain meme or phrase. They use it so often that it becomes old and unfunny very quickly. The meme-killer is especially bad when using the meme incorrectly.

John: 'How was dinner?'
Tim: 'Feels good man.'
John: 'Shut the fuck up already you meme-killer.'

meme-killer by four1111s July 27, 2011

mimekiller 

A person, normally who was sexually violated by a mime at a very young age, who takes out their pent up anger and aggression on minority groups-- usually mimes.

That mimekiller likes to refer to anyone of Iraqi descent as a hodgie.

mimekiller by Animalball Brasky October 30, 2008

Memekiller 

Someone who ruins a meme by overusing it, giving it a bad rep, making bad jokes about it, etc.

Marcus: Dude Joseph is such a memekiller,
Julio: Yeah he fucked up autism memes forever
Joseph: *Commits suicide

Memekiller by papafrank_;-; June 5, 2016