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Irritable Jowel Syndrome

A chronic disease suffered by a good friend of mine. Symptoms include yakking it up when he should be keeping his pie-hole shut.
Ken:Hey Norm, remember the time you, me & the 3 Mormon chicks....
Norm: Hey Ken, STFU! My wife's right here and doesn't need to hear about how I banged that Morman every day for 2 straight months in a row! You f*ing have irritable jowel syndrome, dude~~
Irritable Jowel Syndrome by Bangboy December 26, 2009
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Irritable Jowl Syndrome 

When someone's jaw swings back and forth after going mental on Pills, MDMA, MKAT or Amphetamines.
Check out Paddy's irritable jowl syndrome! He must have necked at least 3 blue Lacosts.