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Usually pronounced as "Guidooooneee", emphasis on the "o". Guidone is an Italian name, a nickname for it is Guido, even though the name Guidone is a good enough name and doesnt need a nickname. A person from the Guidone descent is the cool kid at school, hott, everyone wants to be their friend cuz they are where the party's at. The essence of cool.
Yo, Guidone you comin tonight?
mhmmm biznatch
sweet!
Guidone by 832457 September 2, 2008
Related Words

guidoness 

having the swagger of a guido
kevin b

Kevin- "Damn, get off me shawty"

Corey- " Kevin you and your guidoness are something else"
guidoness by thefallstonguido June 15, 2009