Columbian Mustache Share definition Flag The effect of having traces of cocaine visible on your upper lip after snorting the drug. Bro, wipe away that Columbian Mustache before you leave the bathroom. Columbian Mustache by Michael Wolstencroft February 14, 2006 0 0 Get merch Get the Columbian Mustache mug. Buy Now — $32.95 See more merch