Knuckle Mustard Share definition Flag The residue left on your finger when your hand strikes a turd as you reach back to wipe your heiney. My hand hit the water when I reached back to wipe my ass and came up with knuckle mustard Knuckle Mustard by manofsteel249 January 25, 2011 0 0 Get merch Get the Knuckle Mustard mug. Buy Now — $32.95 See more merch