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Italian for Madonna or Mother of God. Pronounced "marhonne". Usually used as an exclamation. "Oh, Hell!"
"Jimmy, you let the sauce boil over!! What's wrong wit you? Madone!"

"Madone, he's got a mouth on him."
madonne by Sass August 19, 2004
Related Words

Piovono madonne 

Typically italian word used when you get hurt on something ( ex. on your pinkie) and you start saying very bad words.
PIOVONO MADONNE is literally "they're raining the Virgin with child and Saints"
Piovono madonne by italianslug August 13, 2015