cutey pie Share definition Flag A cutey pie is a quarter pound of something and by something it is usually marijuana. Guy 1: Hey, you go to the northside and stock up yet? Guy 2: Yea, I got a whole cutey pie. cutey pie by Phillip Kaltenbach June 27, 2006 0 0 Get merch Get the cutey pie mug. Buy Now — $32.95 See more merch