1. most commonly used in the DMV area, referring to when someone/something is irritating you or annoying to you.
2. most commonly used down south referring to a female. just a southern way of saying "girl" (gurl)
ex: Marcus was acting so dumb last night, so i had my guh face on.
ex2: I'd be guh as sh*t if tomorrow wasn't Friday.
ex: what's up guh?
ex2: boy1: ay you kno Shay? boy2: oh yea that's my guh right thea.