1 definition by misspseudonym

1. When you're so high on certain substances that you mess up your brain.

2. If someone is making your brain hurt either by lying, manipulating, bitching, stressing you out etc.
1. Me and my mate got so skull fucked last night!
Oh my god I'm so skull fucked right now.

2. I just found out my boyfriend is sleeping around. My head's a mess. I feel totally skull fucked.
by misspseudonym January 27, 2016
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