(v.) Hit on, flirt with and/or try to pick up girls.
Bill: "Dude, what're we gonna do tonight?"
Ted: "The usual, cruise chicks, what else?"
(v.) Talking to a female in the effort to have sex with her, i.e. get her out of her underwear.
1. "Man, I hate going out with Ted, he always spends the whole night trying to work panties!"
2. A: "Have you seen Ted?"
B: "Yeah, he's over in the corner over there talking to that chick, working panties."