1 definition by TwitchyPuppy

Usually a female of whatever nationality, whose name is unknown and looking like she’s been on meth her entire life.

A convenient combination between “Methamphetamine” and “Melanie”.

They are often seen on mugshots or roaming in ghettos.
- Hey dude, look! That’s the mugshot of girl who stole my car!
- Damn she looks like a Methanie XD
by TwitchyPuppy April 27, 2019
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