Definitions by Smigslovesyou101

D.U.F.F. 

D-dumb
U-ugly
F-fat
F-friend

or

D-dumb
U-unreasonable
F-fuck
F-face

Go with it as you wish.

Snooki: "Oh my God. What a D.U.F.F.!"
Deena: "I know, right? Totally a duff."

D.U.F.F. by Smigslovesyou101 April 13, 2011