1 definition by Shenpai

When a Lee Sin player feels an intense need to take the second part of his 'q' ability. This is usually caused by a brief decrease in brain function or overall being from the lower tiers on the League of Legends ladder.
Guy 1:Why did that Lee Sin take that 'q'?
Guy 2: It was Lee Syndrome man.
by Shenpai January 29, 2018
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