The effect produced by the climax of one's overly excited enjoyment, usually through the use of illegal substances.
Dude 1: What the fuck is that guy doing??
Dude 2: If your talking about the guy butt fucking that fire hydrant, he's twizzin'. He just railed 5 lines of coke.
Dude 2: If your talking about the guy butt fucking that fire hydrant, he's twizzin'. He just railed 5 lines of coke.
by MyRealNameIsBLUMPKIN June 17, 2010