Definitions by Matthias Drake

Run, bitch, run 

One of the most basic terms in ebonics, this is essential to know. The word bitch is not necessarily derogatory in this case. Usually used to coax a laugh out of one's homies.

See Jane run. Run, bitch, run (for your life)!
~Sinfest

Run, bitch, run by Matthias Drake May 27, 2006