Definitions by Masterpuker

Puke Nuke 

A massive explosion of vomit, covering several rooms, coming from a wasted guy/girl after a night of heavily drinking.

Friend: Wow, it smells! What happened?

Dude: I totally made a Puke Nuke last night.

Friend: Wicked!

Puke Nuke by Masterpuker November 3, 2010